Abstract ID: A27
Abstract Title: Efficacy of Periprostatic Local Anesthetic for Prostate Biopsy Analgesia: a Meta-analysis
Authors: Jones C1, Carter H2, Hanna M3, Wu C4
The Johns Hopkins University Baltimore MD 1, The Johns Hopkins University Baltimore MD 2, The Johns Hopkins University Baltimore MD 3, The Johns Hopkins University Baltimore MD 4
Poster Type: Poster
ABSTRACT BODY
Introduction:
Not all randomized controlled trials examining the analgesic efficacy of periprostatic block with local anesthetic consistently demonstrate a beneficial analgesic effect. We performed a meta-analysis of available randomized trials investigating the analgesic efficacy of periprostatic block with local anesthetic.
Materials and Methods:
The National Library of Medicine's PubMed database was searched for the time period 1966 to August 16, 2005 for all relevant articles. Inclusion criteria included subjects undergoing prostate biopsy, trials that were randomized with one arm of the randomization using local anesthetic for periprostatic block prior to prostate biopsy, and where the assessment of biopsy pain was measured and available in a form compatible for statistical analysis in our meta-analysis.
Results:
Our search resulted in 107 abstracts of which a total of 16 articles met all inclusion criteria. There were 660 subjects who received local anesthetics for a periprostatic block and 616 subjects who did not. The weighted mean difference between the groups indicates that subjects receiving local anesthetic periprostatic block would have a statistically lower pain score compared to those who did not (weighted mean difference in visual analog pain of -1.66 [95% confidence interval = -2.03 to -1.29).
Discussion:
Our meta-analysis suggests that periprostatic block with local anesthetic for prostate biopsy may result in significantly lower levels of pain during the biopsy procedure. Since periprostatic block with local anesthetic is relatively easy to administer and does not appear to be associated with increased morbidity, clinicians performing prostate biopsies should consider utilizing this technique on a routine basis.
ATTACHED FILES
Reg Anesth Pain Med 2005; 30(3):A27