8th Annual Comprehensive Review of Pain Management

August 2-5, 2001
Hyatt Newporter
Newport Beach, CA

Thursday, August 2, 2001

 

Moderator: F. Michael Ferrante, MD

7:00 am

Continental Breakfast with Exhibitors
Mechanisms and Neuropathic Pain

8:00 am

Mechanisms of Tissue Injury Pain States Tony L. Yaksh, PhD
This lecture will identify the advances and the current understanding of the organization of the afferent pathways through which injury-induced input is processed. These insights will consider the physiology of the primary afferents, anatomy of the dorsal horn, ascending pathways, and the thalamic and cortical projections. In addition, the pharmacology of the peripheral and central terminals of the primary afferent will be reviewed. Central nervous system mechanisms related to the regulation of sensory processing will also be reviewed. Specific receptor systems to be considered include those which suppress (and produce analgesia: opioids and a2) and facilitate (produce hyperalgesia: glutamate), nociceptive transmission.

9:00 am Mechanisms of Neuropathic Pain
Tony L. Yaksh, PhD
This lecture will review the peripheral and central (spinal) sequelae associated with compression/section of the peripheral nerve. Specific attention will be focused on the origin of spontaneous activity and chemical sensitivity in the injured axon, the role of growth factors, sympathetic innervation of the injury site and the dorsal root ganglion, sprouting within the central nervous system and the preclinical pharmacology associated with these organizational changes after nerve injury.
10:00 am Break with Exhibitors
10:30 am Pharmacologic Mechanisms of Common Analgesics (NSAIDs, Opioids, Antidepressants, Anticonvulsants, a-Adrenergic Agents)
Tony L. Yaksh, PhD
This lecture will review the pharmacologic basics underlining the use of opioids, antidepressants, anticonvulsants and a-adrenergic agents.
11:15 am

Clinical Neuropathic Pain States (including Postherpetic Neuralgia and CRPS)
James P. Rathmell, MD
This lecture will promote an understanding of pathophysiologic and clinical distinctions between neuropathic and nociceptive pain. The attendee will gain increased familiarity with several neuropathic pain syndromes. This lecture will also attempt to integrate a discussion of pharmacologic and anesthetic approaches used in the treatment of various neuropathic pain states into the body of the lecture.

12:00 noon Lunch on your own
1:00 pm Local Anesthetics
Vincent W.S. Chan, MD, FRCPC
At the conclusion of this lecture, the registrant should be able to:
• Review local anesthetic pharmacology and pharmacokinetics
• Describe recent advances in local anesthetics
• Outline clinical use in pain management
• Review systemic local anesthetic toxicity
2:00 pm Sympathetic Blocks
James P. Rathmell, MD
This lecture will review the anatomy of the stellate ganglion and lumbar paravertebral sympathetic chain. Intravenous phentolamine will also be discussed. The indications and techniques of sympathetic nerve blocks will be addressed. The science of sympathetic nerve blockade will be reviewed.
3:00 pm Break with Exhibitors
3:30 pm Spinal Cord Stimulation
James P. Rathmell, MD
This lecture will evaluate the role of spinal neurostimulator techniques in the management of pain. The hypothesized mechanisms of action will be presented. Equipment, surgical techniques and implantation methods will also be discussed.
  Workshop-2hrs
(Rathmell, Ferrante) 		  Problem-based Learning - 1 hr each (Rosenquist, Kim)

4:45 pm

Sympathetic Blocks - Neurolytic Blocks for Cancer
Pain - 2 hrs
(Limited to 25 Registrants) 		4:45 pm CRPS - 1 hr (Limited to 10 Registrants)
    5:45 pm PHN - 1 hr (Limited to 10 Registrants)
 


Table of Contents | Friday Program