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Local Anesthetic Systemic Toxicity

The American Society of Regional Anesthesia and Pain Medicine (ASRA) periodically updates its practice advisories and associated cognitive aids. The 2020 version of the ASRA Local Anesthetic Systemic Toxicity checklist was created in response to user feedback, simulation studies, and advances in medical knowledge. This report presents the 2020 version and discusses the rationale for its update.

UPDATE 12/1/2020

Please note: This is checklist (versus 1.1) contains additional clarification regarding use of propofol. 

Copyright © 2020 by the American Society of Regional Anesthesia and Pain Medicine, which hereby grants practitioners the right to reproduce the checklist graphic as part of a clinical system for managing LAST. Formats suitable for reproduction and lamination can be obtained at www.asra.com free of charge.

Scholarly publication of these recommendations should be cited as: Neal et al Publication or reproduction of the checklist for commercial use requires written permission from ASRA. Graphic: Erin J. Neal. ACLS, Advanced Cardiac Life Support; LAST, Local Anesthetic Systemic Toxicity.

Publication of these recommendations requires written permission from ASRA


Download the full printable checklist (PDF)

Request other formats (eg, JPG, PNG) by contacting us at asraassistant@asra.com.

Read Special Article (Regional Anesthesia & Pain Medicine, November 2020)