Module 1: Pain Pathways is now available. 



For additional resources on pain pathways, view our full module



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Review Articles & Guides on Acute and Chronic Pain Topics


Acute Pain

Basic Anatomy and Physiology of Pain Pathways (login/cost to view entire article)
Sarah Bourne, MD; Andre G. Machado, MD, PhD; Sean J. Nagel, MD

Clinical Application of Opioid Equianalgesic Data (login/cost to view entire article)
Arnold R Gammaitoni, PharmD; Perry Fine, MD; Nancy Alvarez, PharmD; Mary Lynn McPherson, PharmD; Suzette Bergmark 

Monitoring for Opioid-Induced Respiratory Depression
Rajnish K. Gupta, MD; David A. Edwards, MD, PhD

Multimodal Analgesia and Alternatives to Opioids for Postoperative Analgesia
Veena Graff, MD; Taras Grosh, MD

Perioperative Surgical Home and the Integral Role of Pain Medicine 
Tessa L. Walters, MD;  Edward R. Mariano, MD, MAS; J. David Clark, MD, PhD 

Persistent Postsurgical Pain: Pathophysiology and Preventative Pharmacologic Considerations
Philippe RichebĂ©, MD, PhD; Xavier Capdevila, MD, PhD; Cyril Rivat, PhD

Chronic Pain 

Advanced Innovations for Pain 
Tim J. Lamer, MD; Timothy R. Deer, MD; Salim M. Hayek, MD, PhD   

CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016 
Deborah Dowell, MD, MPH; Tamara M. Haegerich, PhD; Roger Chou, MD 

Pain and Opioids in Cancer Care: Benefits, Risks, and Alternatives 
Mike Bennett, MD, FRCP, FFPMRCA; Judith A. Paice, PhD, RN; Mark Wallace, MD 

Landmark Research Studies in Acute and Chronic Pain


Acute Pain 

New Persistent Opioid Use After Minor and Major Surgical Procedures in US Adults
Chad M. Brummett, MD; Jennifer F. Waljee, MD, MPH, MS; Jenna Goesling, PhD; Stephanie Moser, PhD; Paul Lin, MS; Michael J. Englesbe, MD; Amy S. B. Bohnert, PhD, MHS; Sachin Kheterpal, MD, MBA; Brahmajee K. Nallamothu, MD, MPH

Risks of Developing Persistent Opioid Use After Major Surgery
Neilesh Soneji, MD; Hance A. Clarke, MD, PhD, FRCPC; Dennis T. Ko, MD, MSc; Duminda N. Wijeysundera, MD, PhD

Regional Anesthesia 

The Risk of Falls After Total Knee Arthroplasty with the Use of a Femoral Nerve Block Versus an Adductor Canal Block: A Double-Blinded Randomized Controlled Study 
Elkassabany, Nabil M. MD, MSCE; Antosh, Sean MD; Ahmed, Moustafa MD; Nelson, Charles MD; Israelite, Craig MD; Badiola, Ignacio MD; Cai, Lu F. MD; Williams, Rebekah BS; Hughes, Christopher MPT; Mariano, Edward R. MD, MAS; Liu, Jiabin MD, PhD 

Chronic Pain 

Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain
Erin E. Krebs, MD, MPH; Amy Gravely, MA; Sean Nugent, BA; Agnes C. Jensen, MPH; Beth DeRonne, PharmD; Elizabeth S. Goldsmith, MD, MS; Kurt Kroenke, MD; Matthew J. Bair; Siamak Noorbaloochi, PhD

If you would like to suggest a free or open-access article that contributes to the foundation of pain medicine and would benefit medical students or residents, submit it to us via email:


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